In a recent study from the Dana-Farber Cancer Institute, unplanned weight loss was also found to be associated with an increased risk of cancers of the upper gastrointestinal tract (including esophageal, stomach, liver, and pancreatic cancers), and hematologic cancers such as leukemia, indicating that individuals with unexplained weight loss should consult a physician.
2. Constant fatigue and weakness

Fatigue associated with serious diseases such as cancer is chronic and not relieved by sleep, and research show that unexplained chronic fatigue is one of the most frequent symptoms experienced before cancer diagnosis.
In one study, almost half of the patients diagnosed with cancer reported chronic fatigue in the months preceding the diagnosis.
Some cancers are more likely than others to cause this type of chronic fatigue. Blood cancers such as leukemia and lymphoma can affect the body’s ability to produce normal blood cells, which can lead to extreme fatigue. Colon or stomach cancer may cause slow internal bleeding and anemia, which also results in fatigue. Liver cancer can affect the body’s metabolism, making fatigue a significant symptom.
3. Skin Changes
